We have some incredible country two-laners out here. They seemingly go on forever;gorgeous scenery, lots of elevation challenges. Only one problem...bicyclists and pedestrians are the enemy. You're a nuisance or bother to motorists. What I've found living all over the country is that the cops have to enforce bicyclist and pedestrian right-a-ways against motorists. If they don't, you might as well paint a bullseye on your chest and back.
Most smaller town that have a big college or two support bicyclists & pedestrians and the fines are steep to motorists who don't yield to them. That's still not a 100% foolproof system, but it makes the danger a lot more manageable. On these two-laners, I've had people deliberately run me off the road, throw bottles at me, spit at me etc, etc. I finally found one segment that I feel safe on....only one. I even know a lot of the people who live way out on that road.
I ride with traffic and I use a mirror on the bike. I use many bikes though and they're not all fitted with mirrors. I'll probably come to regret that someday.
Riding against traffic, if the unthinkable should happen, you're dust. Riding with traffic, you can be clipped and possibly survive. I'll take my chances riding with traffic any day over against.
Kevin